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Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory

During the past 15 years, several genetically altered mouse models of human Alzheimer’s disease (AD) have been developed. These costly models have greatly facilitated the evaluation of novel therapeutic approaches. Injecting synthetic β-amyloid (Aβ) 1-42 species into different parts of the brain of...

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Kasza, Ágnes, Penke, Botond, Frank, Zsuzsanna, Bozsó, Zsolt, Szegedi, Viktor, Hunya, Ákos, Németh, Klaudia, Kozma, Gábor, Fülöp, Lívia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150403/
https://ncbi.nlm.nih.gov/pubmed/29156571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22112007
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