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Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory

During the past 15 years, several genetically altered mouse models of human Alzheimer’s disease (AD) have been developed. These costly models have greatly facilitated the evaluation of novel therapeutic approaches. Injecting synthetic β-amyloid (Aβ) 1-42 species into different parts of the brain of...

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Vydáno v:Molecules
Hlavní autoři: Kasza, Ágnes, Penke, Botond, Frank, Zsuzsanna, Bozsó, Zsolt, Szegedi, Viktor, Hunya, Ákos, Németh, Klaudia, Kozma, Gábor, Fülöp, Lívia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150403/
https://ncbi.nlm.nih.gov/pubmed/29156571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22112007
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