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Revisiting glucose metabolism in cancer: lessons from a PKM knock-in model
Isoform selection of pyruvate kinase M (PKM), a glycolytic enzyme, influences fates of glucose-derived carbons in cellular metabolic networks. We recently developed novel mouse lines to study PKM isoform function and identified PKM1 as a potential target in a subset of human lung cancers. This work...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149909/ https://ncbi.nlm.nih.gov/pubmed/30250920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1472054 |
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