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Targeting endosomal pH for cancer chemotherapy

Altered pH homeostasis in cancer cells has been linked with essentially all classical hallmarks of cancer, including chemoresistance. We recently identified a conceptually novel mechanism for how dysregulated pH in hypoxic cells causes chemoresistance which is based on the aberrant cellular distribu...

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Publicado en:Mol Cell Oncol
Autores principales: Lucien, Fabrice, Lavoie, Roxane R., Dubois, Claire M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149877/
https://ncbi.nlm.nih.gov/pubmed/30250892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1435184
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