(−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners

Heat shock proteins (Hsps), amongst them, Hsp70 and Hsp90 families, serve mainly as facilitators of protein folding (molecular chaperones) of the cell. The Hsp70 family of proteins represents one of the most important molecular chaperones in the cell. Plasmodium falciparum, the main agent of malaria...

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Publicado no:Molecules
Main Authors: Zininga, Tawanda, Ramatsui, Lebogang, Makhado, Pertunia Bveledzani, Makumire, Stanley, Achilinou, Ikechukwu, Hoppe, Heinrich, Dirr, Heini, Shonhai, Addmore
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149709/
https://ncbi.nlm.nih.gov/pubmed/29206141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22122139
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