(−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners

Heat shock proteins (Hsps), amongst them, Hsp70 and Hsp90 families, serve mainly as facilitators of protein folding (molecular chaperones) of the cell. The Hsp70 family of proteins represents one of the most important molecular chaperones in the cell. Plasmodium falciparum, the main agent of malaria...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Zininga, Tawanda, Ramatsui, Lebogang, Makhado, Pertunia Bveledzani, Makumire, Stanley, Achilinou, Ikechukwu, Hoppe, Heinrich, Dirr, Heini, Shonhai, Addmore
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149709/
https://ncbi.nlm.nih.gov/pubmed/29206141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22122139
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