Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70

Heat shock protein 70 (Hsp70) is a molecular chaperone that plays an important role in cellular proteostasis. Hsp70s are also implicated in the survival and pathogenicity of malaria parasites. The main agent of malaria, Plasmodium falciparum, expresses six Hsp70s. Of these, two (PfHsp70-1 and PfHsp7...

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Vydáno v:Cell Stress Chaperones
Hlavní autoři: Zininga, Tawanda, Pooe, Ofentse J., Makhado, Pertunia B., Ramatsui, Lebogang, Prinsloo, Earl, Achilonu, Ikechukwu, Dirr, Heinrich, Shonhai, Addmore
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2017
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573689/
https://ncbi.nlm.nih.gov/pubmed/28455613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0797-6
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