Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70

Heat shock protein 70 (Hsp70) is a molecular chaperone that plays an important role in cellular proteostasis. Hsp70s are also implicated in the survival and pathogenicity of malaria parasites. The main agent of malaria, Plasmodium falciparum, expresses six Hsp70s. Of these, two (PfHsp70-1 and PfHsp7...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Zininga, Tawanda, Pooe, Ofentse J., Makhado, Pertunia B., Ramatsui, Lebogang, Prinsloo, Earl, Achilonu, Ikechukwu, Dirr, Heinrich, Shonhai, Addmore
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573689/
https://ncbi.nlm.nih.gov/pubmed/28455613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0797-6
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