Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70

Heat shock protein 70 (Hsp70) is a molecular chaperone that plays an important role in cellular proteostasis. Hsp70s are also implicated in the survival and pathogenicity of malaria parasites. The main agent of malaria, Plasmodium falciparum, expresses six Hsp70s. Of these, two (PfHsp70-1 and PfHsp7...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stress Chaperones
Prif Awduron: Zininga, Tawanda, Pooe, Ofentse J., Makhado, Pertunia B., Ramatsui, Lebogang, Prinsloo, Earl, Achilonu, Ikechukwu, Dirr, Heinrich, Shonhai, Addmore
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Netherlands 2017
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573689/
https://ncbi.nlm.nih.gov/pubmed/28455613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0797-6
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