Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70

Heat shock protein 70 (Hsp70) is a molecular chaperone that plays an important role in cellular proteostasis. Hsp70s are also implicated in the survival and pathogenicity of malaria parasites. The main agent of malaria, Plasmodium falciparum, expresses six Hsp70s. Of these, two (PfHsp70-1 and PfHsp7...

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Bibliografski detalji
Izdano u:Cell Stress Chaperones
Glavni autori: Zininga, Tawanda, Pooe, Ofentse J., Makhado, Pertunia B., Ramatsui, Lebogang, Prinsloo, Earl, Achilonu, Ikechukwu, Dirr, Heinrich, Shonhai, Addmore
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2017
Teme:
Original Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573689/
https://ncbi.nlm.nih.gov/pubmed/28455613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0797-6
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