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Starving PTEN-deficient prostate cancer cells thrive under nutrient stress by scavenging corpses for their supper
Our recent work demonstrates that inactivating mutations in phosphatase and tensin homolog (PTEN) are sufficient to drive macropinocytosis in the context of AMP-activated protein kinase (AMPK) activation. Given that blocking macropinocytosis limits PTEN-deficient prostate tumor growth, AMPK or phosp...
Enregistré dans:
| Publié dans: | Mol Cell Oncol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149707/ https://ncbi.nlm.nih.gov/pubmed/30250923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1472060 |
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