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Starving PTEN-deficient prostate cancer cells thrive under nutrient stress by scavenging corpses for their supper
Our recent work demonstrates that inactivating mutations in phosphatase and tensin homolog (PTEN) are sufficient to drive macropinocytosis in the context of AMP-activated protein kinase (AMPK) activation. Given that blocking macropinocytosis limits PTEN-deficient prostate tumor growth, AMPK or phosp...
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| Udgivet i: | Mol Cell Oncol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149707/ https://ncbi.nlm.nih.gov/pubmed/30250923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1472060 |
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