Dismissal of RNA Polymerase II Underlies a Large Ligand-induced Enhancer Decommissioning Program

Nuclear receptors induce both transcriptional activation and repression programs responsible for development, homeostasis and disease. Here, we report a previously overlooked enhancer decommissioning strategy underlying a large estrogen receptor alpha (ERα)-dependent transcriptional repression progr...

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Publicado en:Mol Cell
Autores principales: Tan, Yuliang, Jin, Chunyu, Ma, Wubin, Hu, Yiren, Tanasa, Bogdan, Oh, Soohwan, Gamliel, Amir, Ma, Qi, Yao, Lu, Zhang, Jie, Ohgi, Kenny, Liu, Wen, Aggarwal, Aneel K, Rosenfeld, Michael G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149533/
https://ncbi.nlm.nih.gov/pubmed/30118678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.07.039
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