Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

Defining mechanisms that maintain tissue stem cells during homeostasis, stress and aging, is important for improving tissue regeneration and repair, and enhancing cancer therapies. Here we show Id1 is induced in hematopoietic stem cells (HSCs) by cytokines that promote HSC proliferation and differen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stem Cell
Prif Awduron: Singh, Satyendra K., Singh, Shweta, Gadomski, Stephen, Sun, Lei, Pfannenstein, Alexander, Valentin, Magidson, Chen, Xiongfong, Kozlov, Serguei, Tessarollo, Lino, Klarmann, Kimberly D., Keller, Jonathan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149219/
https://ncbi.nlm.nih.gov/pubmed/30082068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.001
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