Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

Defining mechanisms that maintain tissue stem cells during homeostasis, stress and aging, is important for improving tissue regeneration and repair, and enhancing cancer therapies. Here we show Id1 is induced in hematopoietic stem cells (HSCs) by cytokines that promote HSC proliferation and differen...

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Vydáno v:Cell Stem Cell
Hlavní autoři: Singh, Satyendra K., Singh, Shweta, Gadomski, Stephen, Sun, Lei, Pfannenstein, Alexander, Valentin, Magidson, Chen, Xiongfong, Kozlov, Serguei, Tessarollo, Lino, Klarmann, Kimberly D., Keller, Jonathan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149219/
https://ncbi.nlm.nih.gov/pubmed/30082068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.001
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