Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

Defining mechanisms that maintain tissue stem cells during homeostasis, stress and aging, is important for improving tissue regeneration and repair, and enhancing cancer therapies. Here we show Id1 is induced in hematopoietic stem cells (HSCs) by cytokines that promote HSC proliferation and differen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Stem Cell
Egile Nagusiak: Singh, Satyendra K., Singh, Shweta, Gadomski, Stephen, Sun, Lei, Pfannenstein, Alexander, Valentin, Magidson, Chen, Xiongfong, Kozlov, Serguei, Tessarollo, Lino, Klarmann, Kimberly D., Keller, Jonathan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149219/
https://ncbi.nlm.nih.gov/pubmed/30082068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.001
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