1,25(OH)(2)D(3) and dexamethasone additively suppress synovial fibroblast activation by CCR6(+) T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade

BACKGROUND: Despite recent improvements in the treatment of rheumatoid arthritis (RA), an insufficient treatment response and the development of treatment resistance in many patients illustrates the need for new therapeutic strategies. Chronic synovial inflammation could be suppressed by targeting R...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Dankers, Wendy, González-Leal, Claudia, Davelaar, Nadine, Asmawidjaja, Patrick S., Mus, Adriana M. C., Hazes, Johanna M. W., Colin, Edgar M., Lubberts, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148958/
https://ncbi.nlm.nih.gov/pubmed/30236152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1706-9
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