Interleukin‐17A Is Produced by CD4+ but Not CD8+ T Cells in Synovial Fluid Following T Cell Receptor Activation and Regulates Different Inflammatory Mediators Compared to Tumor Necrosis Factor in a Model of Psoriatic Arthritis Synovitis

OBJECTIVE: Interleukin‐17A (IL‐17A) and tumor necrosis factor (TNF) contribute to the pathogenesis of psoriatic arthritis (PsA). However, their functional relationship in PsA synovitis has not been fully elucidated. Additionally, although CD8+ T cells in PsA have been recognized via flow cytometry a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Arthritis Rheumatol
Main Authors: Xu, Xiaofei, Davelaar, Nadine, Mus, Anne‐Marie, Asmawidjaja, Patrick S., Hazes, Johanna M. W., Baeten, Dominique L. P., Vis, Marijn, Bisoendial, Radjesh J., Prens, Errol P., Lubberts, Erik
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2020
נושאים:
Psoriatic Arthritis
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497075/
https://ncbi.nlm.nih.gov/pubmed/32243724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41271
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