Inference of Germline Mutational Status and Evaluation of Loss of Heterozygosity in High-Depth, Tumor-Only Sequencing Data

PURPOSE: Inherited germline defects are implicated in up to 10% of human tumors, with particularly well-known roles in breast and ovarian cancers that harbor BRCA1/2-mutated genes. There is also increasing evidence for the role of germline alterations in other malignancies such as colon and pancreat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCO Precis Oncol
Egile Nagusiak: Khiabanian, Hossein, Hirshfield, Kim M., Goldfinger, Mendel, Bird, Simon, Stein, Mark, Aisner, Joseph, Toppmeyer, Deborah, Wong, Serena, Chan, Nancy, Dhar, Kalyani, Gheeya, Jinesh, Vig, Hetal, Hadigol, Mohammad, Pavlick, Dean, Ansari, Sepand, Ali, Siraj, Xia, Bing, Rodriguez-Rodriguez, Lorna, Ganesan, Shridar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Clinical Oncology 2018
Gaiak:
Original Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148761/
https://ncbi.nlm.nih.gov/pubmed/30246169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00148
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak