Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development

Notch1 signaling must elevate to high levels in order to drive the proliferation of CD4(−)CD8(−) double-negative (DN) thymocytes and progression to the CD4(+)CD8(+) double-positive (DP) stage through β-selection. During this critical phase of pre–T-cell development, which is also known as the DN-DP...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Wang, Qing, Yan, Ran, Pinnell, Nancy, McCarter, Anna C., Oh, Yeonjoo, Liu, Yiran, Sha, Cher, Garber, Noah F., Chen, Yitong, Wu, Qingqing, Ku, Chia-Jui, Tran, Ivy, Serna Alarcon, Amparo, Kuick, Rork, Engel, James Douglas, Maillard, Ivan, Cierpicki, Tomasz, Chiang, Mark Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Immunobiology and Immunotherapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148450/
https://ncbi.nlm.nih.gov/pubmed/30076146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-835850
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