ENaC activity in the cortical collecting duct of HKα(1) H(+),K(+)-ATPase knockout mice is uncoupled from Na(+) intake

Modulation of the epithelial Na(+) channel (ENaC) activity in the collecting duct (CD) is an important mechanism for normal Na(+) homeostasis. ENaC activity is inversely related to dietary Na(+) intake, in part due to inhibitory paracrine purinergic regulation. Evidence suggests that H(+),K(+)-ATPas...

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Bibliographic Details
Published in:Am J Physiol Renal Physiol
Main Authors: Mironova, Elena, Lynch, I. Jeanette, Berman, Jonathan M., Gumz, Michelle L, Stockand, James D., Wingo, Charles S.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148313/
https://ncbi.nlm.nih.gov/pubmed/28179253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00401.2016
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