MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

Glycine N-methyltransferase (GNMT) is the most abundant methyltransferase in the liver and a master regulator of the transmethylation flux. GNMT downregulation leads to loss of liver function progressing to fibrosis, cirrhosis, and hepatocellular carcinoma. Moreover, GNMT deficiency aggravates chole...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Fernández-Ramos, David, Fernández-Tussy, Pablo, Lopitz-Otsoa, Fernando, Gutiérrez-de-Juan, Virginia, Navasa, Nicolás, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Simón, Jorge, Fernández, Agustín F., Arbelaiz, Ander, Aransay, Ana M., Lavín, José Luis, Beraza, Naiara, Perugorria, María J., Banales, Jesus M., Villa, Erica, Fraga, Mario F., Anguita, Juan, Avila, Matias A., Berasain, Carmen, Iruzibieta, Paula, Crespo, Javier, Lu, Shelly C., Varela-Rey, Marta, Mato, José M., Delgado, Teresa C., Martínez-Chantar, María L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148053/
https://ncbi.nlm.nih.gov/pubmed/30237481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1014-y
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