MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

Glycine N-methyltransferase (GNMT) is the most abundant methyltransferase in the liver and a master regulator of the transmethylation flux. GNMT downregulation leads to loss of liver function progressing to fibrosis, cirrhosis, and hepatocellular carcinoma. Moreover, GNMT deficiency aggravates chole...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fernández-Ramos, David, Fernández-Tussy, Pablo, Lopitz-Otsoa, Fernando, Gutiérrez-de-Juan, Virginia, Navasa, Nicolás, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Simón, Jorge, Fernández, Agustín F., Arbelaiz, Ander, Aransay, Ana M., Lavín, José Luis, Beraza, Naiara, Perugorria, María J., Banales, Jesus M., Villa, Erica, Fraga, Mario F., Anguita, Juan, Avila, Matias A., Berasain, Carmen, Iruzibieta, Paula, Crespo, Javier, Lu, Shelly C., Varela-Rey, Marta, Mato, José M., Delgado, Teresa C., Martínez-Chantar, María L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148053/
https://ncbi.nlm.nih.gov/pubmed/30237481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1014-y
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