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Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues

An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compo...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lanver, Andreas, Schmalz, Hans-Günther
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147686/
https://ncbi.nlm.nih.gov/pubmed/18007322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/10020508
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