Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation

Transcription factor nuclear factor kappa B (NF-κB) regulates cellular responses to environmental cues. Many stimuli induce NF-κB transiently, making time-dependent transcriptional outputs a fundamental feature of NF-κB activation. Here we show that NF-κB target genes have distinct kinetic patterns...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Zhao, Mingming, Joy, Jaimy, Zhou, Weiqiang, De, Supriyo, Wood, William H., Becker, Kevin G., Ji, Hongkai, Sen, Ranjan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147668/
https://ncbi.nlm.nih.gov/pubmed/30199532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006347
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