Age-associated changes in basal NF-κB function in human CD4(+) T lymphocytes via dysregulation of PI3 kinase

Immune impairment and high circulating level of pro-inflammatory cytokines are landmarks of human aging. However, the molecular basis of immune dys-regulation and the source of inflammatory markers remain unclear. Here we demonstrate that in the absence of overt cell stimulation gene expression medi...

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Udgivet i:Aging (Albany NY)
Main Authors: Bektas, Arsun, Zhang, Yongqing, Lehmann, Elin, Wood, William H., Becker, Kevin G., Madara, Karen, Ferrucci, Luigi, Sen, Ranjan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276789/
https://ncbi.nlm.nih.gov/pubmed/25553802
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