Exogenous C-type natriuretic peptide restores normal growth and prevents early growth plate closure in its deficient rats

Signaling by C-type natriuretic peptide (CNP) and its receptor, natriuretic peptide receptor-B, is a pivotal stimulator of endochondral bone growth. We recently developed CNP knockout (KO) rats that exhibit impaired skeletal growth with early growth plate closure. In the current study, we further ch...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Hirota, Keisho, Furuya, Mayumi, Morozumi, Naomi, Yoshikiyo, Kazunori, Yotsumoto, Takafumi, Jindo, Toshimasa, Nakamura, Ryuichi, Murakami, Koichiro, Ueda, Yohei, Hanada, Takeshi, Sade, Hiroko, Yoshida, Sayaka, Enomoto, Kei, Kanai, Yugo, Yamauchi, Ichiro, Yamashita, Takafumi, Ueda-Sakane, Yoriko, Fujii, Toshihito, Yasoda, Akihiro, Inagaki, Nobuya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147488/
https://ncbi.nlm.nih.gov/pubmed/30235256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204172
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg