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Synthesis and Antitumor Activity of 5-Trifluoromethyl-2,4-dihydropyrazol-3-one Nucleosides
2,4-Dihydropyrazole glucosides 3a-3c were prepared and tested for their antitumor activity. The structures of these compounds were established by (1)H and (13)C-NMR spectroscopy. Glucoside 3b shows an in vitro IC(50) value of 16.4 µM against proliferation of the human promyelotic leukemia (HL60) cel...
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| Publicado en: | Molecules |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6147422/ https://ncbi.nlm.nih.gov/pubmed/18007415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/90300109 |
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