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A one-pot synthesis of 3-trifluoromethyl-2-isoxazolines from trifluoromethyl aldoxime

Functionalized 3-trifluoromethyl-2-isoxazolines and 3-trifluoromethylisoxazoles were easily prepared from trifluoromethyl aldoxime 2 under mild conditions by using DIB as oxidant. Theoretical studies of the reactivity of trifluoroacetonitrile oxide 4 toward olefins and alkynes were carried out. The...

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Detalhes bibliográficos
Main Authors: Gonçalves, Raoni S B, Dos Santos, Michael, Bernadat, Guillaume, Bonnet-Delpon, Danièle, Crousse, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869255/
https://ncbi.nlm.nih.gov/pubmed/24367404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.275
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