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One-pot multistep mechanochemical synthesis of fluorinated pyrazolones

Solventless mechanochemical synthesis represents a technique with improved sustainability metrics compared to solvent-based processes. Herein, we describe a methodical process to run one solventless reaction directly into another through multistep mechanochemistry, effectively amplifying the solvent...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Howard, Joseph L, Nicholson, William, Sagatov, Yerbol, Browne, Duncan L
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629391/
https://ncbi.nlm.nih.gov/pubmed/29062413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.189
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