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Synthesis of new triazole-based trifluoromethyl scaffolds
Trifluoromethyl propargylamines react with various azide derivatives to afford 1,4-disubstituted 1,2,3-triazoles through a Huisgen 1,3-dipolar cycloaddition. The reaction is catalyzed by a Cu(I) species in acetonitrile, and the corresponding products are obtained in good yields. This process thus of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2486457/ https://ncbi.nlm.nih.gov/pubmed/18941482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.4.19 |
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