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Synthesis and Antiproliferative Activity of Triazoles Based on 2-Azabicycloalkanes

A library of 21 novel chiral 1,2,3-triazole-based 2-azabicycloalkane conjugates was designed and synthesized using the copper(I)-catalyzed click reaction. The obtained hybrids were assessed for their antiproliferative potency against three selected human cancer cell lines: Hs294T (melanoma), MIA PaC...

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Vydáno v:Materials (Basel)
Hlavní autoři: Steppeler, Franz, Kłopotowska, Dagmara, Wietrzyk, Joanna, Wojaczyńska, Elżbieta
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072719/
https://ncbi.nlm.nih.gov/pubmed/33919613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma14082039
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