Structural Determinants of the Stability of Enzyme‐Responsive Polyion Complex Nanoparticles Targeting Pseudomonas aeruginosa’s Elastase

Here, we report how the stability of polyion complex (PIC) particles containing Pseudomonas aeruginosa’s elastase (LasB) degradable peptides and antimicrobial poly(ethylene imine) is significantly improved by careful design of the peptide component. Three LasB‐degradable peptides are reported herein...

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Vydáno v:ChemNanoMat
Hlavní autoři: Insua, Ignacio, Petit, Marion, Blackman, Lewis D., Keogh, Robert, Pitto‐Barry, Anaïs, O'Reilly, Rachel K., Peacock, Anna F. A., Krachler, Anne Marie, Fernandez‐Trillo, Francisco
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146907/
https://ncbi.nlm.nih.gov/pubmed/30263883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnma.201800054
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