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Structural Determinants of the Stability of Enzyme‐Responsive Polyion Complex Nanoparticles Targeting Pseudomonas aeruginosa’s Elastase

Here, we report how the stability of polyion complex (PIC) particles containing Pseudomonas aeruginosa’s elastase (LasB) degradable peptides and antimicrobial poly(ethylene imine) is significantly improved by careful design of the peptide component. Three LasB‐degradable peptides are reported herein...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ChemNanoMat
Main Authors: Insua, Ignacio, Petit, Marion, Blackman, Lewis D., Keogh, Robert, Pitto‐Barry, Anaïs, O'Reilly, Rachel K., Peacock, Anna F. A., Krachler, Anne Marie, Fernandez‐Trillo, Francisco
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146907/
https://ncbi.nlm.nih.gov/pubmed/30263883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnma.201800054
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