Structural Determinants of the Stability of Enzyme‐Responsive Polyion Complex Nanoparticles Targeting Pseudomonas aeruginosa’s Elastase

Here, we report how the stability of polyion complex (PIC) particles containing Pseudomonas aeruginosa’s elastase (LasB) degradable peptides and antimicrobial poly(ethylene imine) is significantly improved by careful design of the peptide component. Three LasB‐degradable peptides are reported herein...

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Detalhes bibliográficos
Publicado no:ChemNanoMat
Main Authors: Insua, Ignacio, Petit, Marion, Blackman, Lewis D., Keogh, Robert, Pitto‐Barry, Anaïs, O'Reilly, Rachel K., Peacock, Anna F. A., Krachler, Anne Marie, Fernandez‐Trillo, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146907/
https://ncbi.nlm.nih.gov/pubmed/30263883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnma.201800054
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