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Structural Determinants of the Stability of Enzyme‐Responsive Polyion Complex Nanoparticles Targeting Pseudomonas aeruginosa’s Elastase

Here, we report how the stability of polyion complex (PIC) particles containing Pseudomonas aeruginosa’s elastase (LasB) degradable peptides and antimicrobial poly(ethylene imine) is significantly improved by careful design of the peptide component. Three LasB‐degradable peptides are reported herein...

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發表在:ChemNanoMat
Main Authors: Insua, Ignacio, Petit, Marion, Blackman, Lewis D., Keogh, Robert, Pitto‐Barry, Anaïs, O'Reilly, Rachel K., Peacock, Anna F. A., Krachler, Anne Marie, Fernandez‐Trillo, Francisco
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146907/
https://ncbi.nlm.nih.gov/pubmed/30263883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnma.201800054
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