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JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells
BACKGROUND: HTLV-1 is a retrovirus that infects over 20 million people worldwide and is responsible for the hematopoietic malignancy adult T cell leukemia (ATL). We previously demonstrated that Notch is constitutively activated in ATL cells. Activating genetic mutations were found in Notch; however,...
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| Veröffentlicht in: | J Hematol Oncol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6146899/ https://ncbi.nlm.nih.gov/pubmed/30231940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0665-6 |
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