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Current views on the role of Notch signaling and the pathogenesis of human leukemia

The Notch signaling pathway is highly conserved from Drosophila to humans and plays an important role in the regulation of cellular proliferation, differentiation and apoptosis. Constitutive activation of Notch signaling has been shown to result in excessive cellular proliferation and a wide range o...

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Bibliografiske detaljer
Main Authors: Pancewicz, Joanna, Nicot, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262490/
https://ncbi.nlm.nih.gov/pubmed/22128846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-502
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