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Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1–associated adult T-cell leukemia

The Notch signaling pathway plays an important role in cellular proliferation, differentiation, and apoptosis. Unregulated activation of Notch signaling can result in excessive cellular proliferation and cancer. Human T-cell leukemia virus type 1 (HTLV-I) is the etiological agent of adult T-cell leu...

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Detalhes bibliográficos
Main Authors: Pancewicz, Joanna, Taylor, John M., Datta, Abhik, Baydoun, Hicham H., Waldmann, Thomas A., Hermine, Olivier, Nicot, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944748/
https://ncbi.nlm.nih.gov/pubmed/20823234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010722107
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