Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells

Peptidylarginine deiminase (PAD) enzymes convert histone arginine residues into citrulline to modulate chromatin organization and gene expression. Although PADs are expressed in anterior pituitary gland cells, their functional role and expression in pituitary adenomas are unknown. To begin to addres...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: DeVore, Stanley B., Young, Coleman H., Li, Guangyuan, Sundararajan, Anitha, Ramaraj, Thiruvarangan, Mudge, Joann, Schilkey, Faye, Muth, Aaron, Thompson, Paul R., Cherrington, Brian D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146832/
https://ncbi.nlm.nih.gov/pubmed/29987187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00084-18
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