Expression of the Vaccinia Virus Antiapoptotic F1 Protein Is Blocked by Protein Kinase R in the Absence of the Viral E3 Protein

Poxviruses encode many proteins with the ability to regulate cellular signaling pathways. One such protein is the vaccinia virus innate immunity modulator E3. Multiple functions have been ascribed to E3, including modulating the cellular response to double-stranded RNA, inhibiting the NF-κB and IRF3...

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Vydáno v:J Virol
Hlavní autoři: Mehta, Ninad, Enwere, Emeka K., Santos, Theodore Dos, Saffran, Holly A., Hazes, Bart, Evans, David, Barry, Michele, Smiley, James R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146792/
https://ncbi.nlm.nih.gov/pubmed/29997208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01167-18
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