Engineered Dengue Virus Domain III Proteins Elicit Cross-Neutralizing Antibody Responses in Mice

Dengue virus is the most globally prevalent mosquito-transmitted virus. Primary infection with one of four cocirculating serotypes (DENV-1 to -4) causes a febrile illness, but secondary infection with a heterologous serotype can result in severe disease, due in part to antibody-dependent enhancement...

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Bibliographic Details
Published in:J Virol
Main Authors: Frei, Julia C., Wirchnianski, Ariel S., Govero, Jennifer, Vergnolle, Olivia, Dowd, Kimberly A., Pierson, Theodore C., Kielian, Margaret, Girvin, Mark E., Diamond, Michael S., Lai, Jonathan R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146717/
https://ncbi.nlm.nih.gov/pubmed/29976679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01023-18
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