Mouse Norovirus Infection Reduces the Surface Expression of Major Histocompatibility Complex Class I Proteins and Inhibits CD8(+) T Cell Recognition and Activation

Human noroviruses are highly infectious single-stranded RNA (ssRNA) viruses and the major cause of nonbacterial gastroenteritis worldwide. With the discovery of murine norovirus (MNV) and the introduction of an effective model for norovirus infection and replication, knowledge about infection mechan...

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Bibliographic Details
Published in:J Virol
Main Authors: Fritzlar, Svenja, Jegaskanda, Sinthujan, Aktepe, Turgut Esad, Prier, Julia Emiley, Holz, Lauren Elise, White, Peter A., Mackenzie, Jason M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146715/
https://ncbi.nlm.nih.gov/pubmed/29976673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00286-18
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