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Vulnerability and resilience to Alzheimer’s disease: early life conditions modulate neuropathology and determine cognitive reserve

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with a high prevalence among the elderly and a huge personal and societal impact. Recent epidemiological studies have indicated that the incidence and age of onset of sporadic AD can be modified by lifestyle factors suc...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Lesuis, Sylvie L., Hoeijmakers, Lianne, Korosi, Aniko, de Rooij, Susanne R., Swaab, Dick F., Kessels, Helmut W., Lucassen, Paul J., Krugers, Harm J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145191/
https://ncbi.nlm.nih.gov/pubmed/30227888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0422-7
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