A preclinical perspective on the enhanced vulnerability to Alzheimer's disease after early-life stress

Stress experienced early in life (ES), in the form of childhood maltreatment, maternal neglect or trauma, enhances the risk for cognitive decline in later life. Several epidemiological studies have now shown that environmental and adult life style factors influence AD incidence or age-of-onset and e...

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Pubblicato in:Neurobiol Stress
Autori principali: Hoeijmakers, Lianne, Lesuis, Sylvie L., Krugers, Harm, Lucassen, Paul J., Korosi, Aniko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Article from the Special Issue on "Stress and the Pathogenesis of Alzheimer’s Disease"; Edited by Hongxin Dong, John Csernansky
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991337/
https://ncbi.nlm.nih.gov/pubmed/29888312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2018.02.003
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