Microglial Priming and Alzheimer’s Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?

Neuroinflammation is thought to contribute to Alzheimer’s disease (AD) pathogenesis that is, to a large extent, mediated by microglia. Given the tight interaction between the immune system and the brain, peripheral immune challenges can profoundly affect brain function. Indeed, both preclinical and...

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書目詳細資料
發表在:Front Hum Neurosci
Main Authors: Hoeijmakers, Lianne, Heinen, Yvonne, van Dam, Anne-Marie, Lucassen, Paul J., Korosi, Aniko
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2016
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977314/
https://ncbi.nlm.nih.gov/pubmed/27555812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2016.00398
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