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AptaBlocks: Designing RNA complexes and accelerating RNA-based drug delivery systems

RNA-based therapeutics, i.e. the utilization of synthetic RNA molecules to alter cellular functions, have the potential to address targets which are currently out of scope for traditional drug design pipelines. This potential however hinges on the ability to selectively deliver and internalize thera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Wang, Yijie, Hoinka, Jan, Liang, Yong, Adamus, Tomasz, Swiderski, Piotr, Przytycka, Teresa M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144873/
https://ncbi.nlm.nih.gov/pubmed/29986050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky577
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