Structural dynamics of translation elongation factor Tu during aa-tRNA delivery to the ribosome

The GTPase elongation factor EF-Tu delivers aminoacyl-tRNAs to the mRNA-programmed ribosome during translation. Cognate codon-anticodon interaction stimulates GTP hydrolysis within EF-Tu. It has been proposed that EF-Tu undergoes a large conformational change subsequent to GTP hydrolysis, which resu...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Kavaliauskas, Darius, Chen, Chunlai, Liu, Wei, Cooperman, Barry S, Goldman, Yale E, Knudsen, Charlotte R
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144866/
https://ncbi.nlm.nih.gov/pubmed/30107527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky651
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