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EF-Tu dynamics during pre-translocation complex formation: EF-Tu·GDP exits the ribosome via two different pathways

The G-protein EF-Tu, which undergoes a major conformational change when EF-Tu·GTP is converted to EF-Tu·GDP, forms part of an aminoacyl(aa)-tRNA·EF-Tu·GTP ternary complex (TC) that accelerates the binding of aa-tRNA to the ribosome during peptide elongation. Such binding, placing a portion of EF-Tu...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Liu, Wei, Chen, Chunlai, Kavaliauskas, Darius, Knudsen, Charlotte R., Goldman, Yale E., Cooperman, Barry S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627077/
https://ncbi.nlm.nih.gov/pubmed/26338772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv856
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