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Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance

Cytotoxic CD8(+) T (Tc) cells are the main executors of transformed and cancer cells during cancer immunotherapy. The latest clinical results evidence a high efficacy of novel immunotherapy agents that modulate Tc cell activity against bad prognosis cancers. However, it has not been determined yet w...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Jaime-Sánchez, Paula, Catalán, Elena, Uranga-Murillo, Iratxe, Aguiló, Nacho, Santiago, Llipsy, M Lanuza, Pilar, de Miguel, Diego, A Arias, Maykel, Pardo, Julián
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143514/
https://ncbi.nlm.nih.gov/pubmed/29743559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0112-9
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