Cell death induced by cytotoxic CD8(+) T cells is immunogenic and primes caspase-3–dependent spread immunity against endogenous tumor antigens

BACKGROUND: Elimination of cancer cells by some stimuli like chemotherapy and radiotherapy activates anticancer immunity after the generation of damage‐associated molecular patterns, a process recently named immunogenic cell death (ICD). Despite the recent advances in cancer immunotherapy, very litt...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Jaime-Sanchez, Paula, Uranga-Murillo, Iratxe, Aguilo, Nacho, Khouili, Sofia C, Arias, Maykel A, Sancho, David, Pardo, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174069/
https://ncbi.nlm.nih.gov/pubmed/32241808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000528
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