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Elevated leptin during diet-induced obesity reduces the efficacy of tumor immunotherapy
Various malignancies are reproducibly cured in mouse models, but most cancer immunotherapies show objective responses in a fraction of treated patients. One reason for this disconnect may be the use of young, lean mice lacking immune altering co-morbidities present in cancer patients. While many can...
में बचाया:
| में प्रकाशित: | J Immunol |
|---|---|
| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6143418/ https://ncbi.nlm.nih.gov/pubmed/30135180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701738 |
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