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Effective TRAIL-based immunotherapy requires both plasmacytoid and CD8α dendritic cells

It is now appreciated that there are distinct subsets of dendritic cells (DC) with specialized functions. Plasmacytoid DC (pDC) and CD8α DC can contribute to the priming, activation and function of antitumor CD8 T cells; however, their specific roles and necessity in stimulating antitumor immunity a...

詳細記述

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書誌詳細
主要な著者: James, Britnie R., Brincks, Erik L., Kucaba, Tamara A., Boon, Louis, Griffith, Thomas S.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058344/
https://ncbi.nlm.nih.gov/pubmed/24711083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-014-1548-5
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